Later this week i can post my setup i use with a G700 which has less buttons compared to the naga. I dont use hot bar swapping or shift at all.
Stances on wheel and one instant spell on pushing the wheel.
Standard combos on the thumbstick, 2*BFA and ASFOF and LL. If you want (i dont) bind shift to one of your mouse buttons and you can have all combos you ever need on the thumb, including 3*mystical bane and one debuff combo.