I'm all for this too, although seeing the thread was started at -08 and has 20 pages... Well I have seen stranger things happen. :-)
I play roleplaying games for the story, and try to roleplay my character (weird, I know...). Not being able to help some people to the fullest possible is a bit annoying. I know it's not roleplaying to go and talk only with people with quest indicators over their heads, but most others don't actually talk, which breaks the immersion anyway the same to me.
(And yes, I do refuse to do quests that are against my characters ideals and/or code. That is the reason I have evil and goody-two-shoes characters, as I do want to do every possible quest... ;-) )